Ro4938581 is really a nootropic drug invented in 2009 by a staff Doing the job for Hoffmann-La Roche, which acts as being a subtype-selective inverse agonist in the ?5 subtype of your benzodiazepine binding web page on the GABAA receptor. It has great selectivity for the ?5 subtype and did not create convulsant or anxiogenic consequences in animal